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021-54845833/15800441009
中文名称 : 小鼠抗COPS6单克隆抗体
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Background: |
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IHC |
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Name of antibody: |
COPS6 |
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Immunogen: |
Fusion protein of human COPS6 |
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Full name: |
COP9 signalosome subunit 6 (COPS6) |
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Synonyms: |
CSN6; MOV34-34KD |
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SwissProt: |
Q7L5N1 |
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IHC positive control: |
adenocarcinoma of human colon tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
36 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
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WB Recommended dilution: |
1000-5000 |
