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  • Íÿ¹MYO5A¶à¿Ë¡¿¹Ìå

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ÖÐÎÄÃû³Æ :    Íÿ¹MYO5A¶à¿Ë¡¿¹Ìå



Ó¢ÎÄÃû³Æ :    Anti-MYO5A rabbit polyclonal antibody


±ð        Ãû :    GS1; MYO5; MYH12; MYR12


´¢       ´æ  :     Àä¶³£¨-20¡æ£© ±Ü¹â


¿¹       Ô­ :     MYO5A


ËÞ      Ö÷ :     Rabbit


·´Ó¦ÖÖÊô :    Human


Ïà¹ØÀà±ð :   Ò»¿¹


±ê  ¼Ç Îï :   Unconjugate


¿Ë¡ÀàÐÍ :   Unconjugate


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Background:

This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Applications:

WB

Name of antibody:

MYO5A

Immunogen:

Synthesized peptide derived from C-terminal of human MYO5A.

Full name:

myosin VA (heavy chain 12, myoxin)

Synonyms£º

GS1; MYO5; MYH12; MYR12

SwissProt:

Q9Y4I1

WB Predicted band size:

215 kDa

WB Positive control:

Hela cells lysate

WB Recommended dilution:

500-3000




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