ÖÐÎÄÃû³Æ£º Íÿ¹PIM2¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-PIM2 rabbit polyclonal antibody
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¿¹ Ô£º PIM2
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human, Mouse
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PIM2 |
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Immunogen: |
Fusion protein of human PIM2 |
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Full name: |
pim-2 oncogene |
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SwissProt: |
Q9P1W9 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |

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021-54845833/15800441009
