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中文名称： 兔抗GSK3A/B多克隆抗体
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Background: |
GSK3A encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. GSK3B is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. |
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Applications: |
WB |
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Name of antibody: |
GSK3A/B |
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Immunogen: |
Synthetic peptide of human GSK3A/B |
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Full name: |
glycogen synthase kinase 3 alpha/beta |
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SwissProt: |
P49840/ P49841 |
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WB Predicted band size: |
51/47 kDa |
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WB Positive control: |
TNF-a treated 293 whole cell lysates |
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WB Recommended dilution: |
500-1000 |
