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    • Íÿ¹PIM1¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º  Íÿ¹PIM1¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º  Anti-PIM1 rabbit polyclonal antibody


    ±ð       Ãû£º  PIM


    Ïà¹ØÀà±ð£º  Ò»¿¹


    ´¢      ´æ£º  Àä¶³£¨-20¡æ£©


    ¿¹      Ô­£º  PIM1


    ËÞ      Ö÷£º  Rabbit


    ·´Ó¦ÖÖÊô£º  Human, Mouse, Rat


    ±ê  ¼Ç  Î  Unconjugate


    ¿Ë¡ÀàÐÍ£º  rabbit polyclonal


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    Background:

    The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.

    Applications:

    ELISA, IHC

    Name of antibody:

    PIM1

    Immunogen:

    Fusion protein of human PIM1

    Full name:

    pim-1 oncogene

    Synonyms£º

    PIM

    SwissProt:

    P11309

    ELISA Recommended dilution:

    1000-5000

    IHC positive control:

    Human liver cancer and human thyroid cancer

    IHC Recommend dilution:

    50-200






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