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ÖÐÎÄÃû³Æ£º Íÿ¹PDHB¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-PDHB rabbit polyclonal antibody


±ð      Ãû£º pyruvate dehydrogenase E1 beta subunit; PDHBD; PHE1B; PDHE1B; PDHE1-B


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ËÞ      Ö÷£º Rabbit


¿¹      Ô­£º PDHB


·´Ó¦ÖÖÊô£º Human, Mouse, Rat


±ê  ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal


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Background:

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]

Applications:

ELISA, WB, IHC

Name of antibody:

PDHB

Immunogen:

Fusion protein of human PDHB

Full name:

pyruvate dehydrogenase E1 beta subunit

Synonyms:

PDHBD; PHE1B; PDHE1B; PDHE1-B

SwissProt:

P11177

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

39 kDa

WB Positive control:

Rat heart tissue, Human heart tissue, HepG2 cell lysates

WB Recommended dilution:

1000-5000






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