ÖÐÎÄÃû³Æ£º Íÿ¹PDHB¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-PDHB rabbit polyclonal antibody
±ð Ãû£º pyruvate dehydrogenase E1 beta subunit; PDHBD; PHE1B; PDHE1B; PDHE1-B
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º PDHB
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012] |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PDHB |
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Immunogen: |
Fusion protein of human PDHB |
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Full name: |
pyruvate dehydrogenase E1 beta subunit |
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Synonyms: |
PDHBD; PHE1B; PDHE1B; PDHE1-B |
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SwissProt: |
P11177 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human ovarian cancer |
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IHC Recommend dilution: |
100-300 |
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WB Predicted band size: |
39 kDa |
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WB Positive control: |
Rat heart tissue, Human heart tissue, HepG2 cell lysates |
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WB Recommended dilution: |
1000-5000 |


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