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Background: |
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FPR2 |
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Immunogen: |
Synthetic peptide of human FPR2 |
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Full name: |
formyl peptide receptor 2 |
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Synonyms： |
ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II |
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SwissProt: |
P25090 |
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ELISA Recommended dilution: |
1000-10000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
20-100 |
