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ÖÐÎÄÃû³Æ£ºÍÿ¹CDH8¶à¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-CDH8 rabbit polyclonal antibody

±ð      Ãû£º Nbla04261

¿¹      Ô­£º CDH8

´¢      ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â

ËÞ      Ö÷£º Rabbit

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Human Mouse Rat

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±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º Unconjugate

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Background:

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.

Applications:

WB, IHC, IF

Name of antibody:

CDH8

Immunogen:

Synthesized peptide derived from internal of human CDH8.

Full name:

cadherin 8, type 2

Synonyms£º

Nbla04261

SwissProt:

P55286

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

88 kDa

WB Positive control:

RAW264.7 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

COS7 cells

IF Recommend dilution:

100-500









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