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Background: |
The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
ERAP1 |
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Immunogen: |
Synthetic peptide of human ERAP1 |
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Full name: |
endoplasmic reticulum aminopeptidase 1 |
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Synonyms： |
ALAP; A-LAP; ARTS1; ERAAP; APPILS; ARTS-1; ERAAP1; PILSAP; PILS-AP |
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SwissProt: |
Q9NZ08 |
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ELISA Recommended dilution: |
1000-2000 |
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WB Predicted band size: |
107 kDa |
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WB Positive control: |
Raji cells |
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WB Recommended dilution: |
200-1000 |
