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021-54845833/15800441009
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Background: |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
WDR4 |
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Immunogen: |
Fusion protein of human WDR4 |
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Full name: |
WD repeat domain 4 |
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Synonyms: |
TRM82; TRMT82 |
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SwissProt: |
P57081 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
45 kDa |
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WB Positive control: |
TM4 cell lysate |
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WB Recommended dilution: |
500-2000 |
