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ÖÐÎÄÃû³Æ£ºÍÿ¹SIRT2¶à¿Ë¡¿¹Ìå  

Ó¢ÎÄÃû³Æ£º Anti-SIRT2 rabbit polyclonal antibody

±ð  Ãû£º SIR2; SIR2L; SIR2L2

¿¹  Ô­£º SIRT2

´¢  ´æ£º Àä¶³£¨-20¡æ£©

ËÞ  Ö÷£º Rabbit

Ïà¹ØÀà±ð£º Ò»¿¹

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê¼ÇÎ Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.

Applications:

ELISA, WB

Name of antibody:

SIRT2

Immunogen:

Fusion protein of human SIRT2

Full name:

Sirtuin 2

Synonyms£º

SIR2; SIR2L; SIR2L2

SwissProt:

Q8IXJ6

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

43 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

200-1000




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