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    • Íÿ¹TTI1¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£ºÍÿ¹TTI1¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-TTI1 rabbit polyclonal antibody

    ±ð      Ãû£º smg-10; KIAA0406

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢       ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º Rabbit

    ¿¹      Ô­£º TTI1

    ·´Ó¦ÖÖÊô£º Human, Mouse

    ±ê   ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

    Applications:

    ELISA, IHC

    Name of antibody:

    TTI1

    Immunogen:

    Synthetic peptide of humanTTI1

    Full name:

    TELO2 interacting protein 1

    Synonyms£º

    smg-10; KIAA0406

    SwissProt:

    O43156

    ELISA Recommended dilution:

    2000-10000

    IHC positive control:

    Human prostate cancer and Human esophagus cancer

    IHC Recommend dilution:

    30-150



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