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ÖÐÎÄÃû³Æ£º  Íÿ¹NOD1¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º  Anti-NOD1 rabbit polyclonal antibody


±ð        Ãû£º  CARD4; NLRC1; CLR7.1


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ËÞ       Ö÷£º  Rabbit


¿¹      Ô­£º NOD1


·´Ó¦ÖÖÊô£º  Human, Mouse


±ê  ¼Ç  Î  Unconjugate


¿Ë¡ÀàÐÍ£º  rabbit polyclonal


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Background:

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Applications:

ELISA, IHC

Name of antibody:

NOD1

Immunogen:

Synthetic peptide of human NOD1

Full name:

nucleotide-binding oligomerization domain containing 1

Synonyms£º

CARD4; NLRC1; CLR7.1

SwissProt:

Q9Y239

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer and Human colon cancer

IHC Recommend dilution:

50-200




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