购物车
帮助
021-54845833/15800441009
中文名称：兔抗CRK多克隆抗体
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Background: |
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CRK |
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Immunogen: |
Fusion protein of human CRK |
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Full name: |
v-crk avian sarcoma virus CT10 oncogene homolog |
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Synonyms： |
p38; CRKII |
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SwissProt: |
P46108 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human colon cancer |
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IHC Recommend dilution: |
50-200 |
