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021-54845833/15800441009
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Background: |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
DOK2 (Phospho-Tyr299) |
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Immunogen: |
Synthetic peptide of human DOK2 (Phospho-Tyr299) |
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Full name: |
docking protein 2, 56kDa (Phospho-Tyr299) |
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Synonyms： |
p56DOK; p56dok-2 |
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SwissProt: |
O60496 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
56 kDa |
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WB Positive control: |
Jurkat cells treated with insulin |
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WB Recommended dilution: |
500-1000 |
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IF Positive control: |
Hela cells |
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IF Recommended dilution |
100-200 |
