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    • Íÿ¹ABCG5¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º Íÿ¹ABCG5¶à¿Ë¡¿¹Ìå

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    Anti-ABCG5 rabbit polyclonal antibody

    ±ð      Ãû£º STSL

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    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º Rabbit

    ¿¹      Ô­£º ABCG5

    ·´Ó¦ÖÖÊô£º Human

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.

    Applications:

    ELISA, IHC

    Name of antibody:

    ABCG5

    Immunogen:

    Synthetic peptide of human ABCG5

    Full name:

    ATP-binding cassette, sub-family G (WHITE), member 5

    Synonyms£º

    STSL

    SwissProt:

    Q9H222

    ELISA Recommended dilution:

    2000-5000

    IHC positive control:

    Human liver cancer

    IHC Recommend dilution:

    25-100



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