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中文名称： 兔抗ACTL6B多克隆抗体
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Background: |
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ACTL6B |
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Immunogen: |
Fusion protein of human ACTL6B |
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Full name: |
actin like 6B |
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Synonyms: |
ACTL6; BAF53B; arpNalpha |
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SwissProt: |
O94805 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer |
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IHC Recommend dilution: |
50-300 |
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WB Predicted band size: |
47 kDa |
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WB Positive control: |
HepG2, HL60 and K562 cell lysates |
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WB Recommended dilution: |
1000-5000 |
