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Ó¢ÎÄÃû³Æ£º AP1S3 Antigen (Recombinant Protein)

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Fusion protein corresponding to a region derived from 1-104 amino acids of human AP1S3


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Full name:

adaptor related protein complex 1 subunit sigma 3

Synonyms:

PSORS15

Swissprot:

Q96PC3

Gene Accession:

BC021898

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants.


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