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中文名称：ATG4D抗原（重组蛋白）
英文名称： ATG4D Antigen (Recombinant Protein)
别 名： APG4D; AUTL4; APG4-D
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 334-474 amino acids of human ATG4D |
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Full name: |
autophagy related 4D, cysteine peptidase |
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Synonyms: |
APG4D; AUTL4; APG4-D |
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Swissprot: |
Q86TL0 |
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Gene Accession: |
BC007639 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. |
