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    CAMK2B Antigen (Recombinant Protein)

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    Fusion protein corresponding to a region derived from 14-272 amino acids of human CAMK2B


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    Full name:

    Calcium/calmodulin-dependent protein kinase type II subunit beta

    Synonyms:

    CAM2, CAMK2, CAMKB

    Swissprot:

    Q13554

    Gene Accession:

    BC019070

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.


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