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中文名称：FBH1 抗原（重组蛋白）
英文名称： FBH1 Antigen (Recombinant Protein)
别 名： F-box DNA helicase 1; Fbx18; hFBH1; FBXO18
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 844-1043 amino acids of human FBH1 |
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Full name: |
F-box DNA helicase 1 |
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Synonyms: |
Fbx18; hFBH1; FBXO18 |
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Swissprot: |
Q8NFZ0 |
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Gene Accession: |
BC032674 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
