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    ÖÐÎÄÃû³Æ£º RARA¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º RARA Antigen (Recombinant Protein)

    ±ð       Ãû£º RAR; NR1B1

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    Fusion protein corresponding to a region derived from 200-419 amino acids of human RARA

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    Full name:

    Retinoic acid receptor, alpha

    Synonyms:

    RAR; NR1B1

    Swissprot:

    P10276

    Gene Accession:

    BC008727

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

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