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021-54845833/15800441009
中文名称：MYOT抗原（重组蛋白）
英文名称： MYOT Antigen (Recombinant Protein)
别 名： MFM3; TTID; TTOD; LGMD1; LGMD1A
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 299-498 amino acids of human MYOT |
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Full name: |
myotilin |
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Synonyms: |
MFM3; TTID; TTOD; LGMD1; LGMD1A |
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Swissprot: |
Q9UBF9 |
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Gene Accession: |
BC005376 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
