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    ÖÐÎÄÃû³Æ£º MR1 ¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º MR1 Antigen (Recombinant Protein)

    ±ð     Ãû£º  major histocompatibility complex, class I-related; HLALS

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    Fusion protein corresponding to a region derived from 110-257 amino acids of human MR1

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    Full name:

    major histocompatibility complex, class I-related

    Synonyms:

    HLALS

    Swissprot:

    Q95460

    Gene Accession:

    BC012485

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.



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