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Fusion protein corresponding to a region derived from 1-148 amino acids of human PTP4A3 |
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Full name: |
protein tyrosine phosphatase 4A3 |
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Synonyms: |
PRL3; PRL-3; PRL-R |
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Swissprot: |
O75365 |
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Gene Accession: |
BC003105 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. |
