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Ó¢ÎÄÃû³Æ£º Anti-MAP2K4 rabbit polyclonal antibody
±ð Ãû£º JNKK; MEK4; MKK4; SEK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º MAP2K4
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background:
This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
Applications:
WB
Name of antibody:
MAP2K4
Immunogen:
Synthetic peptide of human MAP2K4
Full name:
mitogen-activated protein kinase kinase 4
Synonyms£º
JNKK; MEK4; MKK4; SEK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1
SwissProt:
P45985
WB Predicted band size:
44 kDa
WB Positive control:
HUVEC cells
WB Recommended dilution:
500-1000

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021-54845833/15800441009
