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Background: |
Transcriptional factor that can act as an activator or repressor depending on isoform and/orpost-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping. |
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Applications: |
WB |
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Name of antibody: |
SP3/4 |
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Immunogen: |
Synthesized peptide derived from C-terminal of human SP3/4. |
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Full name: |
Sp3 transcription factor/Sp4 transcription factor |
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Synonyms： |
SPR2/HF1B; SPR-1 |
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SwissProt: |
Q02447/Q02446 |
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WB Predicted band size: |
82 kDa |
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WB Positive control: |
Jurkat cells lysate |
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WB Recommended dilution: |
500-3000 |
