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    • Íÿ¹CCDC106¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£ºÍÿ¹CCDC106¶à¿Ë¡¿¹Ìå 

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    Anti-CCDC106 rabbit polyclonal antibody

    ±ð      Ãû£º ZNF581; HSU79303

    Ïà¹ØÀà±ð£º Ò»¿¹

    ¿¹      Ô­£º CCDC106

    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º
    Rabbit

    ·´Ó¦ÖÖÊô£º Human, Mouse

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

    ¼¼Êõ¹æ¸ñ

    Background:

    The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.

    Applications:

    ELISA, IHC

    Name of antibody:

    CCDC106

    Immunogen:

    Fusion protein of human CCDC106

    Full name:

    coiled-coil domain containing 106

    Synonyms£º

    ZNF581; HSU79303

    SwissProt:

    Q9BWC9

    ELISA Recommended dilution:

    2000-10000

    IHC positive control:

    Human cervical cancer and human colon cancer

    IHC Recommend dilution:

    100-300




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