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ÖÐÎÄÃû³Æ£ºÐ¡Êó¿¹AMACRµ¥¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-AMACR mouse monoclonal antibody

±ð     Ãû £º alpha-methylacyl-CoA racemase; RM; RACE; CBAS4; P504S; AMACRD

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ËÞ      Ö÷£º Mouse

¿¹      Ô­£º AMACR

·´Ó¦ÖÖÊô£º Human, Mouse

±ê   ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º mouse monoclonal

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Background:

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Applications:

WB

Name of antibody:

AMACR

Immunogen:

Fusion protein of human AMACR

Full name:

alpha-methylacyl-CoA racemase

Synonyms:

RM; RACE; CBAS4; P504S; AMACRD

SwissProt:

Q9UHK6

WB Predicted band size:

42 kDa

WB Positive control:

PC3, LNCAP, Hela, HepG2 cell, Mouse kidney tissue, Mouse liver tissue lysates

WB Recommended dilution:

1000-5000


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