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ÖÐÎÄÃû³Æ£º Íÿ¹NBN¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-NBN rabbit polyclonal antibody


±ð       Ãû£º ATV, NBS, P95, NBS1, AT-V1, AT-V2


Ïà¹ØÀà±ð£º Ò»¿¹


´¢       ´æ£º Àä¶³£¨-20¡æ£©


ËÞ       Ö÷£º Rabbit


¿¹       Ô­£º NBN


·´Ó¦ÖÖÊô£º Human, Mouse, Rat


±ê  ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal


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Background:

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Applications:

ELISA, IHC

Name of antibody:

NBN

Immunogen:

Synthetic peptide of human NBN

Full name:

nibrin

Synonyms£º

ATV, NBS, P95, NBS1, AT-V1, AT-V2

SwissProt:

O60934

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and Human lung cancer

IHC Recommend dilution:

25-100





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