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ÖÐÎÄÃû³Æ£º Íÿ¹IL4¶à¿Ë¡¿¹Ìå  

Ó¢ÎÄÃû³Æ£º Anti-IL4 rabbit polyclonal antibody

±ð    Ãû£º BSF1; IL-4; BCGF1; BSF-1; BCGF-1

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ËÞ    Ö÷£º Rabbit

¿¹    Ô­£º IL4

·´Ó¦ÖÖÊô£º Human

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º Unconjugate

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Background:

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Applications:

WB

Name of antibody:

IL4

Immunogen:

Synthesized peptide derived from C-terminal of human IL4.

Full name:

interleukin 4

Synonyms£º

BSF1; IL-4; BCGF1; BSF-1; BCGF-1

SwissProt:

P05112

WB Predicted band size:

17 kDa

WB Positive control:

Hela cells lysate

WB Recommended dilution:

500-3000









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