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中文名称： 兔抗ACHE多克隆抗体
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WB Predicted band size: |
68 kDa |
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WB Positive control: |
Raji cells |
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WB Recommended dilution: |
200-1000 |
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IHC Recommend dilution: |
25-100 |
|
IHC positive control: |
Human liver cancer and Human colon cancer |
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ELISA Recommended dilution: |
1000-2000 |
|
SwissProt: |
P22303 |
|
Synonyms： |
YT; ACEE; ARACHE; N-ACHE |
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Full name: |
acetylcholinesterase |
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Immunogen: |
Synthetic peptide of human ACHE |
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Name of antibody: |
ACHE |
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Applications: |
ELISA, WB, IHC |
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Background: |
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. |
