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中文名称： 兔抗HIF1A多克隆抗体
别 名： HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA
抗 原： HIF1A
储 存： 冷冻（-20℃）
宿 主： Rabbit
标 记 物： Unconjugate
技术规格
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Background: |
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
HIF1A |
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Immunogen: |
Fusion protein of human HIF1A |
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Full name: |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
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Synonyms： |
HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA |
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SwissProt: |
Q16665 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer and human brain |
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IHC Recommend dilution: |
25-10 |
