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Ó¢ÎÄÃû³Æ£º Anti-HDAC8 mouse monoclonal antibody

±ð       Ãû£º histone deacetylase 8; HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1

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ËÞ       Ö÷£º Mouse

¿¹       Ô­£º HDAC8

·´Ó¦ÖÖÊô£º Human

±ê  ¼Ç  Î Unconjugate

¿Ë¡ÀàÐÍ£º mouse monoclonal


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Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

HDAC8

Immunogen:

Fusion protein of human HDAC8

Full name:

histone deacetylase 8

Synonyms:

HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1

SwissProt:

Q9BY41

WB Predicted band size:

42 KD

WB Positive control:

Hela, Molt4, K562, NIH/3T3, 293T and Jurkat cell lysates

WB Recommended dilution:

500-2000

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