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Anti-CD3E rabbit polyclonal antibody

±ð       Ãû£º T3E; TCRE; FLJ18683

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ËÞ      Ö÷£º Rabbit

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CD3E

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Applications:

WB

Name of antibody:

CD3E

Immunogen:

Synthetic peptide of human CD3E

Full name:

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms£º

T3E; TCRE; FLJ18683

SwissProt:

P07766

WB Predicted band size:

23 kDa

WB Positive control:

Molt4 and Jurkat cells

WB Recommended dilution:

500-1000




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