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中文名称 : 小鼠抗FGG单克隆抗体
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Background: |
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul |
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Applications: |
WB, IF |
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Name of antibody: |
FGG |
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Immunogen: |
Fusion protein of human FGG |
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Full name: |
fibrinogen gamma chain (FGG), transcript variant gamma-A |
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Synonyms: |
fibrinogen, gamma chain; fibrinogen, gamma polypeptide; fibrinogen gamma chain |
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SwissProt: |
P02679 |
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WB Predicted band size: |
52 kDa |
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WB Positive control: |
HepG2 cell lysate |
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WB Recommended dilution: |
500-2000 |
