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      ÖÐÎÄÃû³Æ£ºÐ¡Êó¿¹FERMT3µ¥¿Ë¡¿¹Ìå

      Ó¢ÎÄÃû³Æ£º Anti-FERMT3 mouse monoclonal antibody

      ±ð       Ãû£º fermitin family member 3; URP2; KIND3; MIG-2; MIG2B; URP2SF; UNC112C

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      ËÞ       Ö÷£º Mouse

      ¿¹       Ô­£º FERMT3

      ·´Ó¦ÖÖÊô£º Human

      ±ê  ¼Ç Î Unconjugate

      ¿Ë¡ÀàÐÍ£º mouse monoclonal


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      Background:

      Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

      Applications:

      WB, IHC

      Name of antibody:

      FERMT3

      Immunogen:

      Fusion protein of human FERMT3

      Full name:

      fermitin family member 3

      Synonyms:

      URP2; KIND3; MIG-2; MIG2B; URP2SF; UNC112C

      SwissProt:

      Q86UX7

      IHC positive control:

      Human tonsil tissue

      IHC Recommend dilution:

      50-150

      WB Predicted band size:

      76 KD

      WB Positive control:

      Jurkat cell lysate

      WB Recommended dilution:

      200-1000

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