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  • СÊó¿¹CUL4Bµ¥¿Ë¡¿¹Ìå

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ÖÐÎÄÃû³Æ : СÊó¿¹CUL4Bµ¥¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ : Anti-CUL4B mouse monoclonal antibody

±ð       Ãû : CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

¿¹       Ô­ : CUL4B

´¢       ´æ : Àä¶³£¨-20¡æ£© ±Ü¹â

ËÞ       Ö÷ : Mouse

·´Ó¦ ÖÖÊô : Human , Dog , Mouse

Ïà¹Ø Àà±ð : Ò»¿¹

±ê  ¼Ç  Îï : Unconjugate

¿Ë¡Àà ÐÍ : mouse monoclonal


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Background:

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC

Name of antibody:

CUL4B

Immunogen:

Fusion protein of human CUL4B

Full name:

cullin 4B (CUL4B), transcript variant 1

Synonyms:

CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

SwissProt:

Q13620

IHC positive control:

human pancreas tissue and carcinoma of human pancreas tissue; carcinoma of human thyroid tissue and carcinoma of human prostate tissue

IHC Recommend dilution:

25-100

WB Predicted band size:

104 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, Jurkat, MDCK, MCF-7 cell lysates

WB Recommended dilution:

1000-5000

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