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中文名称：兔抗CLCN4多克隆抗体
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IF Recommend dilution: |
100-500 |
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IF positive control: |
Huvec cells |
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WB Recommended dilution: |
500-3000 |
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WB Positive control: |
MCF-7 cells lysate |
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WB Predicted band size: |
85 kDa |
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SwissProt: |
P51793 |
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Synonyms： |
CLC4; ClC-4; ClC-4A |
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Full name: |
chloride channel, voltage-sensitive 4 |
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Immunogen: |
Synthesized peptide derived from internal of human CLCN4. |
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Name of antibody: |
CLCN4 |
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Applications: |
WB, IF |
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Background: |
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. |
