购物车
帮助
021-54845833/15800441009
中文名称： 兔抗UPF1多克隆抗体
|
Background: |
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
UPF1 |
|
Immunogen: |
Synthetic peptide of human UPF1 |
|
Full name: |
UPF1 RNA helicase and ATPase |
|
Synonyms: |
HUPF1; NORF1; RENT1; smg-2; pNORF1 |
|
SwissProt: |
Q92900 |
|
ELISA Recommended dilution: |
1000-5000 |
|
IHC positive control: |
Human liver cancer and Human thyroid cancer |
|
IHC Recommend dilution: |
50-200 |
|
WB Predicted band size: |
124 kDa |
|
WB Positive control: |
Raji cells |
|
WB Recommended dilution: |
200-1000 |
