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021-54845833/15800441009
中文名称：小鼠抗CBX5单克隆抗体
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Background: |
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
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Applications: |
WB, IF, IHC |
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Name of antibody: |
CBX5 |
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Immunogen: |
Fusion protein of human CBX5 |
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Full name: |
chromobox 5 |
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Synonyms: |
HP1; HP1A; HEL25 |
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SwissProt: |
P45973 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
200-400 |
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WB Predicted band size: |
22 kDa |
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WB Positive control: |
Mouse brain tissue, COS7, C6, 3T3, HelaNE, 293T and MCF7 cell lysates |
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WB Recommended dilution: |
1000-5000 |
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IF positive control: |
Hela cells |
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IF Recommend dilution: |
150-300 |
