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021-54845833/15800441009
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Background: |
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling. |
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Applications: |
WB |
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Name of antibody: |
EPOR(Ab-426) |
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Immunogen: |
Synthesized peptide derived from Internal of human Epo-R. |
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Full name: |
erythropoietin receptor |
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Synonyms： |
EPO-R |
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SwissProt: |
P19235 |
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WB Predicted band size: |
55 kDa |
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WB Positive control: |
Jurkat cells lysate |
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WB Recommended dilution: |
500-3000 |
