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021-54845833/15800441009
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Background: |
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008]. |
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Applications: |
WB, IHC |
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Name of antibody: |
PPT1 |
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Immunogen: |
Fusion protein of human PPT1 |
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Full name: |
palmitoyl-protein thioesterase 1 (PPT1), transcript variant 1 |
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Synonyms: |
CLN1; INCL; PPT |
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SwissProt: |
P50897 |
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IHC positive control: |
carcinoma of human prostate tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
34 kDa |
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WB Positive control: |
HepG2, Hela, A549, COS7, Jurkat, MDCK, MCF-7 cell lysates |
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WB Recommended dilution: |
1000-5000 |
