ÖÐÎÄÃû³Æ£ºÍÿ¹CDK5(Phospho-Tyr15)¶à¿Ë¡¿¹Ìå
¿¹ Ô£º CDK5(Phospho-Tyr15)
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ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human Mouse Rat
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±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º Unconjugate
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Background: |
Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM. |
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Applications: |
WB |
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Name of antibody: |
CDK5(Phospho-Tyr15) |
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Immunogen: |
Peptide sequence around phosphorylation site of Tyrosine15 (G-T-Y(p)-G-T) derived from Human CDK5. |
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Full name: |
cyclin-dependent kinase 5 |
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Synonyms£º |
PSSALRE |
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SwissProt: |
Q00535 |
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WB Predicted band size: |
33 kDa |
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WB Positive control: |
COS7 cells lysates treated with EGF |
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WB Recommended dilution: |
500-1000 |

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021-54845833/15800441009
