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021-54845833/15800441009
中文名称：小鼠抗CASP4单克隆抗体
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Background: |
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB |
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Name of antibody: |
CASP4 |
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Immunogen: |
Fusion protein of human CASP4 |
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Full name: |
caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant gamma |
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Synonyms: |
ICE(rel)II; ICEREL-II; ICH-2; Mih1/TX; TX |
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SwissProt: |
P49662 |
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WB Predicted band size: |
43 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK and MCF7 cell lysates |
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WB Recommended dilution: |
1000-5000 |
