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Ó¢ÎÄÃû³Æ£º UBAP1 Antigen (Recombinant Protein)

±ð     Ãû£º ubiquitin associated protein 1; UAP; UBAP; NAG20; UBAP-1

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Fusion protein corresponding to C terminal 200 amino acids of human UBAP1

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Full name:

ubiquitin associated protein 1

Synonyms:

UAP; UBAP; NAG20; UBAP-1

Swissprot:

Q9NZ09

Gene Accession:

BC098141

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.




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