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Full name: |
2'-5'-oligoadenylate synthetase-like |
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Synonyms: |
OASLd, TRIP14, TRIP-14, p59OASL, p59 OASL, p59-OASL |
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Swissprot: |
Q15646 |
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Gene Accession: |
BC117408 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
OASL encodes an interferon-induced protein that is a member of the 2-5A synthetase family. 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, resulting in general RNA degradation and consequent inhibition of protein synthesis. 2-5As are produced by a well-conserved family of interferon-induced enzymes, the 2-5A synthetases or OASs |
