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中文名称： U2AF2 抗原（重组蛋白）
英文名称： U2AF2 Antigen (Recombinant Protein)
别 名： U2 small nuclear RNA auxiliary factor 2; U2AF65
相关类别：抗原
储 存： 冷冻（-20℃）
概 述
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Full name: |
U2 small nuclear RNA auxiliary factor 2 |
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Synonyms: |
U2AF65 |
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Swissprot: |
P26368 |
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Gene Accession: |
BC008740 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. |
