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中文名称： HSD17B4抗原（重组蛋白）
英文名称： HSD17B4 Antigen (Recombinant Protein)
别 名： DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 484-736 amino acids of human HSD17B4 |
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Full name: |
hydroxysteroid (17-beta) dehydrogenase 4 |
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Synonyms: |
DBP; MFE-2; MPF-2; PRLTS1; SDR8C1 |
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Swissprot: |
P51659 |
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Gene Accession: |
BC003098 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. |
