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中文名称： ESR2抗原（重组蛋白）
英文名称： ESR2 Antigen (Recombinant Protein)
别 名： Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to C terminal 207 amino acids of human ESR2 |
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Full name: |
estrogen receptor 2 (ER beta) |
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Synonyms: |
Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA |
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Swissprot: |
Q92731 |
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Gene Accession: |
BC024181 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. |
